10 Best & Most Unique Airbnb Rentals in South Carolina

Posted by
Brittany Varano
October 27, 2020
Updated April 04, 2022

best airbnbs in south carolina
Photo: Airbnb

We research, evaluate and select travel destinations based on a number of factors, including our writers’ experience, user reviews and more. We may earn a commission when you book or purchase through our links. See our editorial policy to learn more.

A visit to The Palmetto State means a trip filled with southern comforts, subtropical weather, and historical attractions.

And you can enjoy them all while staying in one of the best Airbnbs in South Carolina.

Best known for top U.S. travel destinations like Myrtle Beach, Hilton Head, and Charleston, South Carolina offers travelers a lot in the way of impressive things to do. And you can head there anytime you want, as this beautiful coastal state enjoys mild winters and warm weather most of the year – every month a good month to visit.

During your visit to South Carolina, don’t sleep on the incredible local food, and be sure to try crowd favorites such as shrimp and grits, fried green tomatoes, and South Carolina-style barbecue. And it’s not just mouth-watering cuisine you’ll want to savor.

This state has no shortage of incredible natural sights to enjoy, too. Be sure to add places like Congaree National Park, Francis Marion National Forest, and Huntington Beach State Park to your South Carolina bucket list.

So if seaside beaches and sun-soaked palm tree lounging sound like your kind of adventure, here are the best and most unique Airbnbs in South Carolina for your upcoming trip.

Related Read: 11 Gorgeous Places to Glamp in North Carolina

1. The Majestic Treehouse

south carolina treehouse airbnb rental
Photo: Airbnb

Why you should stay: Luxurious treehouse experience complete with unique amenities and romantic add-ons.

  • Location: Walhalla
  • Sleeps: 2
  • Minimum stay: 2 nights
  • Rates from: $395/night

The Majestic Treehouse is a luxury experience that features an eye-catching mosaic of floor-to-ceiling windows. Natural light pours into the antique-decorated space, where special features like a cozy fireplace, skylights, and a kitchenette ensure you’ll have everything you could need and want. Ramps and bridges lead the way to the home’s entrance, so there’s no need to carry your luggage up steep stairs or steps.

Surrounding the treehouse is an outdoor oasis complete with a fire pit, two-person hammock, outdoor shower, a rope swing bed, and a two-story deck with a dining table and lounge chairs. This South Carolina Airbnb is on Bolt Farms, a spacious property with hiking trails and gardens. You can add on the VIP experience with your stay, which includes a bottle of wine, s’ mores supplies, and more.

Check Availability

Related Read: 9 Gorgeous South Carolina Treehouse Rentals

2. The Cedar Bluff House

Cedar Bluff Cottage SC
Photo: Airbnb

Why you should stay: Picturesque little South Carolina cottage, complete with a full gym.

  • Location: Bluffton
  • Sleeps: 3
  • Minimum stay: 2 nights
  • Rates from: $332/night

The Cedar Bluff House is a beautiful one-bedroom cottage that oozes southern charm tucked behind a gated entrance. Its location on the May River offers calming views and added privacy – not to mention easy access to the water. From the comfort of the home’s backyard, relax on the stone patio complete with rocking chairs, a fire circle, and a grill. There’s also a private dock with kayaks for guest use for those itching to explore the gentle river.

If you can’t stand skipping a day at the gym, the garage features a well-equipped workout area complete with a rowing machine, free weights, exercise bike, treadmill, and more. You’ll also want to spend time in nearby Bluffton, a seaside town with fresh restaurants, a great distillery, and seasonal seas turtle hatchings (be sure to watch from afar!).

Check Availability

Related Read: Top 10 East Coast Vacation Spots You Never Considered (But Should!)

3. Southern Home

south carolina airbnb rental
Photo: Airbnb

Why you should stay: Gorgeous three-bedroom, pet-friendly home in a peaceful neighborhood.

  • Location: Fort Mill
  • Sleeps: 6
  • Minimum stay: 4 nights
  • Rates from: $214/night

This beautifully decorated southern home on the North Carolina border is an excellent option for visitors looking to stay outside Charlotte. It’s 30 minutes from the international airport and 25 minutes from uptown in a quiet neighborhood.

It has a fenced-in yard where your furry friends can run freely and safely. In the evenings, follow the brick pathway to a stone fire circle for s’mores under the night’s sky. The house oozes southern charm, from the cow statues in the kitchen to the pink-and-white color theme in the bedrooms.

If someone in your party needs to get some work done, they can retire to the study and have their own space to focus, even when the home is full.

Check Availability

Related Read: 8 Epic Glamping Destinations In South Carolina

4. Mid-Century Modern Treehouse

luxury south carolina treehouse
Photo: Airbnb

Why you should stay: A treehouse-esque Airbnb with impeccable interior design and private a hot tub.

  • Location: West Columbia
  • Sleeps: 2
  • Minimum stay: 1 night
  • Rates from: $250/night

This bright mid-century modern treehouse tucked just outside of South Carolina’s capital offers guests a retreat in the woods. It’s a charming little home with stylish and trendy decor. You’ll find all the comforts of home here, including a full bathroom, a small but totally capable kitchen, and even espresso machine.

Outside, a hot tub beckons for a luxurious soak after a long day exploring the 10-acre property and surrounding attractions. Adjacent to the hot tub is a spacious front deck with cushioned seating when you need a break from the jets. There’s also a fire pit, a grill, and strung market lights over the deck to illuminate the outside space at night.

Check Availability

5. The Cedar Nest

The Cedar Nest
Photo: Airbnb

Why you should stay: A gorgeous bungalow only miles from downtown Charleston and Sullivan’s Island Beach.

  • Location: Mount Pleasant
  • Sleeps: 2
  • Minimum stay: 3 nights
  • Rates from: $224/night

The Cedar Nest is a beach paradise not far from one of South Carolina’s best beaches and Mount Pleasant’s popular Old Village neighborhood. Surrounded by palm trees, well-manicured gardens, and tiki torches, the outdoor lounge offers a comfortable and stylish place to catch some sun.

And if you work up a sweat, you can rinse off in the privacy of your own wooden rain shower just around the corner from the patio. This is one of the best Airbnbs in South Carolina for people who love outdoor living.

Inside, deep blues and neutral tones are coupled expertly with natural cedar accents to create an exquisitely modern atmosphere. The bedroom has a king bed facing a private fireplace and glass doors that open to the garden. There’s also a kitchenette stocked with the basics and an elegant bathroom with a tiled walk-in shower.

Check Availability

6. The Living Room Treehouse

Living Room Treehouse airbnb
Photo: Airbnb

Why you should stay: Vintage-styled tiny home on stilts surrounded by forest with unique outdoor features.

  • Location: Wadmalaw Island
  • Sleeps: 2
  • Minimum stay: 30 days
  • Rates from: $113/night

One step inside of The Living Room Treehouse, and you’ll immediately feel right at home, thanks to the comforting and lush greenery that fills the home – it’ll likely be the first thing to catch your eye.

But if you’re more of an architecture buff, it could instead be the antique windows and rustic wood walls that draw your attention. But no matter what your style, this bright and loving home is almost certainly going to be a hit. The cheery and stylish living space is expertly designed with wrought iron accents, pops of bright blue, and string lights around the ceiling.

During your stay, indoor amenities such as a mini kitchen, fireplace, board games, and a record player set the scene for a relaxing visit. Outside, spend your days lounging on the rope swing bed, sitting around the campfire, or taking a stroll on the Bolt Farms trails. There’s even a lovely private outdoor shower on the deck.

Check Availability

7. Old House Cay

Old House Cay SC
Photo: Airbnb

Why you should stay: A vacation rental on three private islands accessible only by boat.

  • Location: Hilton Head Island
  • Sleeps: 6
  • Minimum stay: 2 nights
  • Rates from: $425/night

Live like a millionaire at the Old House Cay, an Airbnb experience unlike any other. Sat on three private islands, this South Carolina vacation rental can only be reached by boat. But its a quick ride at only about 10 minutes from Hilton Head.

On the islands, you’ll be surrounded by sweeping views of the sea. Fortunately, this home has plenty of space from which to admire the views and revel in the millionaire lifestyle, like an impressive boardwalk, lookout tower, and cupola.

Other noteworthy amenities include a circular deck with a fire pit, an outdoor shower, and a pier for fishing. The interior of the home has everything you could need during your stay and features three comfortable bedrooms, 2.5 baths, and a spacious kitchen and dining area. With your booking, the hosts will organize your transportation, so don’t sweat it if you don’t know the first thing about steering a boat.

Check Availability

8. Serene Cottage

south carolina home airbnb rental
Photo: Airbnb

Why you should stay: A bright cottage with a saltwater pool near Charleston.

  • Location: Charleston
  • Sleeps: 4
  • Minimum stay: 1 night
  • Rates from: $211/night garden

Make the most of your trip to Charleston in this serene cottage with hotel-style amenities. Behind the home, you’ll find a serene koi pond dotted with lilies, as well as a community heated saltwater pool with sun loungers. After you’ve enjoyed a dip in the pool, you can enter the home via gorgeous wooden french doors that span the exterior wall of the living room.

“The courtyard is a lovely oasis and [this] rental location is close to many neighborhood off-the-beaten-path restaurants, as well as within walking distance to larger attractions in the area,” says Airbnb guest Valerie.

You’ll also be near to local bakeries, boutiques, and more in the Cannonborough Elliotborough neighborhood of Charleston. It’s a young professional neighborhood with a hipster twist, so it has plenty of draws like affordable artisan shops and trendy distilleries.

Check Availability

9. Waterfall Getaway

Waterfall getaway airbnb
Photo: Airbnb

Why you should stay: An architectural gem perched above a waterfall on 100 wooded acres.

  • Location: Westminster
  • Sleeps: 4
  • Minimum stay: 2 nights
  • Rates from: $295/night

Get off the beaten path in this exceptional waterfall getaway designed by architect James H. Fox. You won’t find internet or T.V. here, but instead, a chance to disconnect from the everyday in the pristine surroundings of Fountain Falls.

To fill the time, take a walk along the hiking paths, visit nearby attractions like Riley Moore Falls and Historic Traveler’s Rest State Park, or take a trip to downtown Westminster, just 15 minutes away.

Or better yet, spend your time unwinding inside this concrete, glass, and wooden home. The indoor stone fireplace creates a great place to relax with a loved one, and the balcony and screened-porch boast impressive views of the falls. It feels like a modern version of a Frank Lloyd Wright home and would be a very impressive place to take someone for a surprise birthday or anniversary getaway.

Check Availability

10. South Beach Cottage

South Beach Cottages
Photo: Airbnb

Why you should stay: Vibrant, tropical-inspired cottage within walking distance of Myrtle Beach.

  • Location: Myrtle Beach
  • Sleeps: 10
  • Minimum stay: 2 nights
  • Rates from: $189/night

The South Beach Cottage is a four-bedroom vacation rental perfect for a large group excited to explore the best of Myrtle Beach. Each bedroom has a king or a queen bed, and there’s a pull-out sofa to sleep two more.

The home has a laundry room as well as a balcony overlooking Ocean Blvd. This rainbow lane of cottages is located near popular local attractions like the pier and boardwalk, The Market Common, and the area’s top restaurants.

Myrtle Beach is a classic East Coast beach town, complete with a seaside amusement park, endless options for beach snacks like funnel cakes and thick-cut french fries, a waterpark, arcades, and more than one “Ripely’s Believe it or Not Museum.” It’s an extremely fun place for a family getaway but also a great spot for a fun-loving duo to relieve their teenage beach days.

Check Availability

Find Your Next Getaway

Get epic travel ideas delivered to your inbox with Weekend Wanderer, our newsletter inspiring more than 10,000 readers every week.

Seen in: South Carolina, Southeast, Where to Stay

Find your next adventure

Sign up for Weekend Wanderer and join thousands of readers getting epic travel ideas weekly.

Related Posts