Missouri

12 Unique Airbnbs in Missouri, from St. Louis to the Ozarks

best airbnb rentals in missouri
Photo: Airbnb

Territory Supply is reader-supported and may earn a commission when you book or purchase using our links. If you’re traveling, be sure to check local COVID-19 guidelines ahead of time.


Missouri’s days as the rugged gateway to the western frontier may be long gone, but a slew of eclectic airbnbs are ensuring the next generation can still find plenty of adventurous experiences.

Once the starting point for westward journeys on the Santa Fe, California, and Oregon trails, Missouri is today a bedrock of midwestern music, indulgent food, and outdoor recreation. And one of the best way to explore the hills and highlands of the Show-Me State is by booking one of these unique airbnbs in Missouri, all of which have their own local, unique vibes.

Here are 12 of the best airbnbs in Missouri for every type of traveler no matter what your budget or interests.

Related: 12 Stunning Chicago Vacation Rentals for a Lively Windy City Stay

1. The TreeLoft

TreeLoft at BaseCamp
Photo: Airbnb

Why you should stay: Lots of luxuries lofted in the leaves.

  • Location: Perryville
  • Sleeps: 2
  • Minimum stay: 1 night
  • Rates from: $239/night

Disconnect from the real world and immerse yourself in nature while reliving your childhood days in the TreeLoft at Basecamp. There’s no Wi-Fi or TV and only limited cell service, so your peace and tranquility won’t be interrupted when you stay in this custom-built luxury treehouse. You’ll have lots of privacy as it’s nestled in the woods on a 20-acre farm.

The perfect set up for romance, couples can relax together in the hot tub or cozy up next to the fireplace to watch a movie, do a crossword puzzle, or otherwise spend some quality time together. Afterward, gaze up at the stars through the skylight from your king-sized bed. Before you turn in, be sure to use the remote solar shade so the sun won’t wake you too early. It’s truly one of the more romantic airbnbs in Missouri.

Check Availability

2. Silo Farm Haus

Silo Farm Haus missouri
Photo: Airbnb

Why you should stay: Stay in a funky silo in Ste. Genevieve wine country.

  • Location: Ste. Genevieve
  • Sleeps: 4
  • Minimum stay: 1 night
  • Rates from: $189/night

If you’re looking for a unique stay in a quiet setting, the Silo Farm Haus definitely delivers. A grain silo that was transformed into a rustic, custom designed home, it sits on a 200-acre farm in the heart of wine country. While it can sleep four, it may be best for a couple unless privacy isn’t an issue and two guests don’t mind sleeping on an air mattress in the living room. The bedroom is upstairs, furnished with a queen bed.

Look forward to sipping your coffee from the front porch swing while watching the sun come up, sampling the offerings at area wineries, and enjoying incredible stargazing after dark, far from the city lights.

Check Availability

3. Augusta Haus II

Augusta Haus II missouri airbnb
Photo: Airbnb

Why you should stay: Enjoy your new-found favorite wine on the cute covered porch.

  • Location: Augusta
  • Sleeps: 6
  • Minimum stay: 2 nights
  • Rates from: $232/night

This mid-19th-century home highlights many of its original features while still incorporating modern amenities. Located in the heart of Missouri’s wine country, it’s ideal for wine-loving couples who want to enjoy tasting and touring, and perhaps bring back a bottle to sip in the private screened-in porch off the largest bedroom. Fortunately, it’s also spacious and family-friendly enough for bringing the kids (though they may not want to go wine tasting.)

Guests often comment that chefs are sure to appreciate the sprawling kitchen, though others find the spa-like bathroom to be the highlight of the house.

“Lovely stay. Amazing kitchen space for cooking and visiting. Especially loved the antique shop just a short walk up the street!”

Emily, St. Louis, MO
Check Availability

4. Branson Farmhouse

branson modern farmhouse
Photo: Airbnb

Why you should stay: The perfect stay to explore the town of Branson.

  • Location: Branson
  • Sleeps: 6
  • Minimum stay: 1 night
  • Rates from: $150/night

A perfect location for enjoying the many attractions in Branson, which range from the Dolly Parton Stage Show to a museum housed in a replica of the Titanic, this modern farmhouse-style home is in the heart of the city. Fortunately, it’s on a dead-end street with wooded views, so you get to be near the action but sleep in peace. And as your hosts have lived here their entire life, they can be your insider guides for planning the perfect trip.

A great backyard, a washer and dryer, and all of the usual comforts of home are included, making this one of the best value airbnbs in Missouri, especially for six people.

Check Availability

5. The Ivory Gabel Cabin

Ivory Gabel Cabin
Photo: Airbnb

Why you should stay: Feel some serious safari vibes at this peaceful Ozarks escape.

  • Location: Crane
  • Sleeps: 6
  • Minimum stay: 2 nights
  • Rates from: $150/night

A getaway a bit further from the tourist crowds of Branson, the Ivory Gabel Cabin is a peaceful, private retreat about 40 miles from Branson and 30 miles from Springfield. Enjoying sipping your morning coffee on the front porch before exploring the area, perhaps via floating or paddling on the James River, hiking the nearby scenic trails, or taking a trip out to Lavender Falls. There’s lots to do on the property, too, including outdoor lawn games. It’s one of the better dog-friendly airbnbs in Missouri, too, as there’s just a $35 fee to cover cleaning (but be sure to let the owners know in advance that a pup is coming along.)

The home looks like it was designed for the cover of an architecture magazine, and the surrounding Ozarks are almost as pretty. After a day outside, come back and spend the evening grilling on the deck and cozying up on the patio. Fixings for s’mores are included (along with hot cocoa, games, Wi-Fi and a TV with Netlfix for rainy days.)

Check Availability

6. The Gatsby Penthouse

gatsby penthouse
Photo: Airbnb

Why you should stay: Lux 1930s apartment in the capital city’s tallest residential point.

  • Location: St. Louis
  • Sleeps: 10
  • Minimum stay: 1 night
  • Rates from: $664night

The Gatsby Penthouse only for VIPs – or, at least, people who want to feel like a VIP. Located at the city’s tallest residential building, it covers more than 4,0000 square feet, which helps justify the high cost. Its one of the pricier airbnbs in Missouri but hey, it does sleep a bit group. It also offers 360-degree views of St. Louis, with a terrace on either end of the apartment in case you want to hang out outdoors in the evenings.

A stay here is a stay you won’t soon forget. It’s like stepping both back in time and into another world of high-end, vintage luxury. In fact, the home has been used for numerous photo shoots. And, bonus: you get access to the building’s pool during the summer, which can come in handy on those hot St. Louis afternoons.

Check Availability

7. Midcentury Home on 50 Acres

Frank Lloyd Wright inspired airbnb
Photo: Airbnb

Why you should stay: Splurge on your own private resort.

  • Location: Union
  • Sleeps: 15
  • Minimum stay: 1 night
  • Rates from: $675/night

Looking for a perfect place for a family reunion, a getaway for a large group of friends, or maybe even a corporate retreat? This extra-spacious home was inspired by renowned architect Frank Lloyd Wright and sits on 50 private acres that includes everything from a koi pond to a swimming pool. Union is less than an hour to St. Louis, so it’s easy enough to enjoy activities in the city while still enjoying plenty of space to yourself back at home. It’s also close to Jefferson City, where you can take a tour of the creepy and awesome Missouri State Penitentiary.

Back at the airbnb, you’ll have extras like pool toys, life jackets, beach towels, and everything you’ll need for a day spent closer to home.

Check Availability

8. Prairie Hollow Hideaway

Prairie Hollow Hideaway
Photo: Airbnb

Why you should stay: Sleep in a log cabin like Missouri’s earliest pioneers.

  • Location: Eminence
  • Sleeps: 7
  • Minimum stay: 1 night
  • Rates from: $115/night

This postcard-perfect log cabin may be what you envision when you think about a classic Missouri getaway. It’s a place to slow down and enjoy a more relaxed and in-the-moment lifestyle for a dew days. There’s no TV and few electronics, and while there is technically Wi-Fi, it’s spotty and is best for email and texting, not streaming Netflix. The home is an opportunity to simply enjoy a relaxing experience without the buzz of electronics.

You’ll be close to hikes at nearby Echo Bluff State Bluff or can hang out and enjoy the amenities near the home, like a fire pit, picnic area, creek, and porch swing. There are no other houses in sight, providing plenty of privacy and seclusion. The base price makes it one of the more affordable airbnbs in Missouri, though there’s an extra $10 fee for every guest past the first two.

Check Availability

9. The Aviators Penthouse Loft

The Aviators Penthouse Loft
Photo: Airbnb

Why you should stay: Insanely posh digs near St. Louis’s hottest neighborhood.

  • Location: St. Louis
  • Sleeps: 10
  • Minimum stay: 1 night
  • Rates from: $449/night

This two-bedroom condo is extra-spacious and ultra-luxurious, a penthouse that takes up the entire floor in a building where it’s the only residence. It’s located in the Mid Town Alley area and just a short walk from world-famous Pappy’s Smokehouse. The well-known restaurant is famous for Memphis-style barbecue, including ribs that were named the best in America by the Food Network. The entire neighborhood is super hip and filled with breweries, trendy restaurants, farm markets, and historic buildings.

It’s all about high quality here, from premium linens and Ralph Lauren towels to the amazing beds.

“The most comfortable bed I’ve ever slept on!! My husband and I felt like we were literally floating!”

Arianna, Parkton,NC
Check Availability

10. Hampton’s Waterside Hideaway

Hampton's Waterside Hideaway
Photo: Airbnb

Why you should stay: Perfect for an active and relaxing vacation, complete with kayaks.

  • Location: Innsbrook
  • Sleeps: 10
  • Minimum stay: 2 nights
  • Rates from: $400/night

There’s no need to leave once you get to this beautiful waterfront chalet. It’s a vacation destination of its own, complete with a private dock for fishing, kayaks for paddling around the small lake, and an outdoor fire pit for making s’mores.

If you want to do a little exploring, within a 15-minute drive of the house are sandy swimming beaches and many picturesque hiking trails. The spacious interior includes all the necessities, and you’ll be stunned once you step inside. The dining room looks like a posh restaurant annex, and in addition to a large deck, you also get a private waterfront pier for enjoying sunny summer days.

Check Availability

11. Lakeside A-Frame

lakeside getaway missouri
Photo: Airbnb

Why you should stay: A beach right outside your front door, complete with kayaks and a paddleboat.

  • Location: Innsbrook
  • Sleeps: 8
  • Minimum stay: 2 nights
  • Rates from: $273/night

A gorgeous chalet-style cabin in Innsbrook, this home offers guests a beach just steps front the front door. And the rental includes kayaks, a fishing dock, outdoor swimming pool, a grill and options for outdoor dining. When the weather is pleasant, you can even book a horseback riding tour at the nearby stable. It’s also one of the best dog-friendly airbnbs in Missouri, since you can bring up to two pets (with a small additional cleaning fee.)

“It was a beautiful home stocked with everything we needed and more. We enjoyed mornings on the dock watching the fish and evenings around the campfire!”

Keith & Kristen, Greenwood, MO
Check Availability

12. Modern Farmhouse

modern farmhouse MO
Photo: Airbnb

Why you should stay: Sprawling, lux home near all the summer fun of the Ozarks.

  • Location: Ridgedale
  • Sleeps: 16
  • Minimum stay: 3 nights
  • Rates from: $347/night

Cedarwood Farmstead offers a secluded retreat on eight acres of wilderness in the Ozarks, providing lots of space indoors and outdoors for a large group. It comes with some great amenities that will ensure no one’s ever bored, including multiple tree swings and a zip line. After dark, turn off the lights and relax in the hot tub, gazing up to enjoy the millions of brilliant stars.

Some of the other highlights include a wood-burning fireplace on a large upper deck, entertainment options like a home theater room with seating for large groups, and a pool table. And since you’re in the Ozarks, you’ll have everything from hiking to rafting to floating beach bars at your disposal.

Check Availability

Find Your Next Adventure

Sign up for the Weekend Wanderer and join thousands of readers getting epic travel and Airbnb ideas every week.


Seen in: Midwest, Missouri, Where to Stay, Where to Stay in the Midwest

Find your next adventure

Sign up for Weekend Wanderer and join thousands of readers getting epic travel ideas weekly.

Related Posts